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The dynamic action of SecA during the initiation of protein translocation

The motor ATPase SecA drives protein secretion through the bacterial Sec complex. The PPXD (pre-protein cross-linking domain) of the enzyme has been observed in different positions, effectively opening and closing a clamp for the polypeptide substrate. We set out to explore the implicated dynamic ro...

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Detalles Bibliográficos
Autores principales: Gold, Vicki A. M., Whitehouse, Sarah, Robson, Alice, Collinson, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685266/
https://www.ncbi.nlm.nih.gov/pubmed/23126322
http://dx.doi.org/10.1042/BJ20121314