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The dynamic action of SecA during the initiation of protein translocation
The motor ATPase SecA drives protein secretion through the bacterial Sec complex. The PPXD (pre-protein cross-linking domain) of the enzyme has been observed in different positions, effectively opening and closing a clamp for the polypeptide substrate. We set out to explore the implicated dynamic ro...
Autores principales: | Gold, Vicki A. M., Whitehouse, Sarah, Robson, Alice, Collinson, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685266/ https://www.ncbi.nlm.nih.gov/pubmed/23126322 http://dx.doi.org/10.1042/BJ20121314 |
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