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ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection

Vertebrate DNA can be chemically modified by methylation of the 5 position of the cytosine base in the context of CpG dinucleotides. This modification creates a binding site for MBD (methyl-CpG-binding domain) proteins which target chromatin-modifying activities that are thought to contribute to tra...

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Detalles Bibliográficos
Autores principales: Long, Hannah K., Blackledge, Neil P., Klose, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685328/
https://www.ncbi.nlm.nih.gov/pubmed/23697932
http://dx.doi.org/10.1042/BST20130028