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Preferential D-loop Extension by a Translesion DNA Polymerase Underlies Error-Prone Recombination

Although homologous recombination (HR) is considered an accurate form of DNA repair, genetics suggest that Escherichia coli (E. coli) translesion DNA polymerase (pol) IV (DinB) promotes error-prone recombination during stress which allows cells to overcome adverse conditions. How pol IV functions an...

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Detalles Bibliográficos
Autores principales: Pomerantz, Richard T., Kurth, Isabel, Goodman, Myron F., O'Donnell, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685420/
https://www.ncbi.nlm.nih.gov/pubmed/23686288
http://dx.doi.org/10.1038/nsmb.2573