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Energy, ageing, fidelity and sex: oocyte mitochondrial DNA as a protected genetic template

Oxidative phosphorylation couples ATP synthesis to respiratory electron transport. In eukaryotes, this coupling occurs in mitochondria, which carry DNA. Respiratory electron transport in the presence of molecular oxygen generates free radicals, reactive oxygen species (ROS), which are mutagenic. In...

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Detalles Bibliográficos
Autores principales: de Paula, Wilson B. M., Lucas, Cathy H., Agip, Ahmed-Noor A., Vizcay-Barrena, Gema, Allen, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685464/
https://www.ncbi.nlm.nih.gov/pubmed/23754815
http://dx.doi.org/10.1098/rstb.2012.0263