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Energy, ageing, fidelity and sex: oocyte mitochondrial DNA as a protected genetic template
Oxidative phosphorylation couples ATP synthesis to respiratory electron transport. In eukaryotes, this coupling occurs in mitochondria, which carry DNA. Respiratory electron transport in the presence of molecular oxygen generates free radicals, reactive oxygen species (ROS), which are mutagenic. In...
Autores principales: | de Paula, Wilson B. M., Lucas, Cathy H., Agip, Ahmed-Noor A., Vizcay-Barrena, Gema, Allen, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685464/ https://www.ncbi.nlm.nih.gov/pubmed/23754815 http://dx.doi.org/10.1098/rstb.2012.0263 |
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