Caspase-2 is involved in cell death induction by taxanes in breast cancer cells

BACKGROUND: We studied the role of caspase-2 in apoptosis induction by taxanes (paclitaxel, novel taxane SB-T-1216) in breast cancer cells using SK-BR-3 (nonfunctional p53, functional caspase-3) and MCF-7 (functional p53, nonfunctional caspase-3) cell lines. RESULTS: Both taxanes induced apoptosis i...

Descripción completa

Detalles Bibliográficos
Autores principales: Jelínek, Michael, Balušíková, Kamila, Kopperová, Dana, Němcová-Fürstová, Vlasta, Šrámek, Jan, Fidlerová, Julie, Zanardi, Ilaria, Ojima, Iwao, Kovář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685568/
https://www.ncbi.nlm.nih.gov/pubmed/23672670
http://dx.doi.org/10.1186/1475-2867-13-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685568/
https://www.ncbi.nlm.nih.gov/pubmed/23672670
http://dx.doi.org/10.1186/1475-2867-13-42

Ejemplares similares