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Caspase-2 is involved in cell death induction by taxanes in breast cancer cells

BACKGROUND: We studied the role of caspase-2 in apoptosis induction by taxanes (paclitaxel, novel taxane SB-T-1216) in breast cancer cells using SK-BR-3 (nonfunctional p53, functional caspase-3) and MCF-7 (functional p53, nonfunctional caspase-3) cell lines. RESULTS: Both taxanes induced apoptosis i...

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Detalles Bibliográficos
Autores principales:	Jelínek, Michael, Balušíková, Kamila, Kopperová, Dana, Němcová-Fürstová, Vlasta, Šrámek, Jan, Fidlerová, Julie, Zanardi, Ilaria, Ojima, Iwao, Kovář, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685568/ https://www.ncbi.nlm.nih.gov/pubmed/23672670 http://dx.doi.org/10.1186/1475-2867-13-42

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