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Genetic interaction of GSH metabolic pathway genes in cystic fibrosis

BACKGROUND: Cystic fibrosis (CF) is a monogenic disease caused by CFTR gene mutations, with clinical expression similar to complex disease, influenced by genetic and environmental factors. Among the possible modifier genes, those associated to metabolic pathways of glutathione (GSH) have been consid...

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Detalles Bibliográficos
Autores principales: Marson, Fernando Augusto de Lima, Bertuzzo, Carmen Sílvia, Secolin, Rodrigo, Ribeiro, Antônio Fernando, Ribeiro, José Dirceu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685592/
https://www.ncbi.nlm.nih.gov/pubmed/23758905
http://dx.doi.org/10.1186/1471-2350-14-60