Non-imidazole histamine H(3) ligands: part V. synthesis and preliminary pharmacological investigation of 1-[2-thiazol-4-yl- and 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives

Series of 1-[2-thiazol-4-yl-(2-aminoethyl)]- and 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives have been prepared and in vitro tested as H(3)-receptor antagonists (the electrically evoked contraction of the guinea-pig jejunum). It appeared that by comparison of homologous pairs,...

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Detalles Bibliográficos
Autores principales: Guryn, Roman, Staszewski, Marek, Walczyński, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685697/
https://www.ncbi.nlm.nih.gov/pubmed/23807824
http://dx.doi.org/10.1007/s00044-012-0372-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3685697/
https://www.ncbi.nlm.nih.gov/pubmed/23807824
http://dx.doi.org/10.1007/s00044-012-0372-8

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