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The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock()

The mitochondria-shaping protein optic atrophy 1 (OPA1) has genetically distinguishable roles in mitochondrial morphology and apoptosis. The latter depends on the presenilin associated rhomboid like (PARL) protease, essential for the accumulation of a soluble intermembrane space form of OPA1 (IMS-OP...

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Detalles Bibliográficos
Autores principales: Sanjuán Szklarz, Luiza K., Scorrano, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686154/
https://www.ncbi.nlm.nih.gov/pubmed/22579715
http://dx.doi.org/10.1016/j.bbabio.2012.05.001