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The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock()
The mitochondria-shaping protein optic atrophy 1 (OPA1) has genetically distinguishable roles in mitochondrial morphology and apoptosis. The latter depends on the presenilin associated rhomboid like (PARL) protease, essential for the accumulation of a soluble intermembrane space form of OPA1 (IMS-OP...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Pub. Co
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686154/ https://www.ncbi.nlm.nih.gov/pubmed/22579715 http://dx.doi.org/10.1016/j.bbabio.2012.05.001 |