Nickel inhibits β-1 adrenoceptor mediated activation of cardiac CFTR chloride channels

Cardiac ventricular myocytes exhibit a protein kinase A-dependent Cl(−) current (I(Cl.PKA)) mediated by the cystic fibrosis transmembrane conductance regulator (CFTR). There is conflicting evidence regarding the ability of the divalent cation nickel (Ni(2+)), which has been used widely in vitro in t...

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Detalles Bibliográficos
Autores principales: Barman, Palash P., Cheng, Hongwei, Hancox, Jules C., James, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686155/
https://www.ncbi.nlm.nih.gov/pubmed/23376720
http://dx.doi.org/10.1016/j.bbrc.2013.01.087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686155/
https://www.ncbi.nlm.nih.gov/pubmed/23376720
http://dx.doi.org/10.1016/j.bbrc.2013.01.087

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