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Nickel inhibits β-1 adrenoceptor mediated activation of cardiac CFTR chloride channels

Cardiac ventricular myocytes exhibit a protein kinase A-dependent Cl(−) current (I(Cl.PKA)) mediated by the cystic fibrosis transmembrane conductance regulator (CFTR). There is conflicting evidence regarding the ability of the divalent cation nickel (Ni(2+)), which has been used widely in vitro in t...

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Detalles Bibliográficos
Autores principales:	Barman, Palash P., Cheng, Hongwei, Hancox, Jules C., James, Andrew F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686155/ https://www.ncbi.nlm.nih.gov/pubmed/23376720 http://dx.doi.org/10.1016/j.bbrc.2013.01.087

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