Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes

BACKGROUND: Multiple genes have been implicated by association studies in altering inflammatory bowel disease (IBD) predisposition. Paediatric patients often manifest more extensive disease and a particularly severe disease course. It is likely that genetic predisposition plays a more substantial ro...

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Detalles Bibliográficos
Autores principales: Christodoulou, Katja, Wiskin, Anthony E, Gibson, Jane, Tapper, William, Willis, Claire, Afzal, Nadeem A, Upstill-Goddard, Rosanna, Holloway, John W, Simpson, Michael A, Beattie, R Mark, Collins, Andrew, Ennis, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2013
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686259/
https://www.ncbi.nlm.nih.gov/pubmed/22543157
http://dx.doi.org/10.1136/gutjnl-2011-301833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686259/
https://www.ncbi.nlm.nih.gov/pubmed/22543157
http://dx.doi.org/10.1136/gutjnl-2011-301833

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