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Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins

BACKGROUND: Autophagy is a conserved cellular process that degrades and recycles cytoplasmic components via a lysosomal pathway. The phosphatidylethanolamine (PE)-conjugation of the Atg8 protein plays an important role in the yeast autophagy process. In humans, six Atg8 homologs, including MAP1LC3A,...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Ma, Haijie, Wu, Jiaxue, Huang, Qiang, Liu, Jun O, Yu, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686597/
https://www.ncbi.nlm.nih.gov/pubmed/23721406
http://dx.doi.org/10.1186/1471-2121-14-27