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Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins
BACKGROUND: Autophagy is a conserved cellular process that degrades and recycles cytoplasmic components via a lysosomal pathway. The phosphatidylethanolamine (PE)-conjugation of the Atg8 protein plays an important role in the yeast autophagy process. In humans, six Atg8 homologs, including MAP1LC3A,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686597/ https://www.ncbi.nlm.nih.gov/pubmed/23721406 http://dx.doi.org/10.1186/1471-2121-14-27 |