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Pilot study of PET imaging of (124)I-iodoazomycin galactopyranoside (IAZGP), a putative hypoxia imaging agent, in patients with colorectal cancer and head and neck cancer

BACKGROUND: Hypoxia within solid tumors confers radiation resistance and a poorer prognosis. (124)I-iodoazomycin galactopyranoside ((124)I-IAZGP) has shown promise as a hypoxia radiotracer in animal models. We performed a clinical study to evaluate the safety, biodistribution, and imaging characteri...

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Detalles Bibliográficos
Autores principales: O’Donoghue, Joseph A, Guillem, José G, Schöder, Heiko, Lee, Nancy Y, Divgi, Chaitanya R, Ruby, Jeannine A, Humm, John L, Lee-Kong, Steven A, Burnazi, Eva M, Cai, Shangde, Carlin, Sean D, Leibold, Tobias, Zanzonico, Pat B, Ling, C Clifton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686612/
https://www.ncbi.nlm.nih.gov/pubmed/23731770
http://dx.doi.org/10.1186/2191-219X-3-42