Hypoxia-inducible factor (HIF) network: insights from mathematical models

Oxygen is a crucial molecule for cellular function. When oxygen demand exceeds supply, the oxygen sensing pathway centred on the hypoxia inducible factor (HIF) is switched on and promotes adaptation to hypoxia by up-regulating genes involved in angiogenesis, erythropoiesis and glycolysis. The regula...

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Detalles Bibliográficos
Autores principales: Cavadas, Miguel AS, Nguyen, Lan K, Cheong, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686674/
https://www.ncbi.nlm.nih.gov/pubmed/23758895
http://dx.doi.org/10.1186/1478-811X-11-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686674/
https://www.ncbi.nlm.nih.gov/pubmed/23758895
http://dx.doi.org/10.1186/1478-811X-11-42

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