Cargando…

Hypoxia-inducible factor (HIF) network: insights from mathematical models

Oxygen is a crucial molecule for cellular function. When oxygen demand exceeds supply, the oxygen sensing pathway centred on the hypoxia inducible factor (HIF) is switched on and promotes adaptation to hypoxia by up-regulating genes involved in angiogenesis, erythropoiesis and glycolysis. The regula...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cavadas, Miguel AS, Nguyen, Lan K, Cheong, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686674/ https://www.ncbi.nlm.nih.gov/pubmed/23758895 http://dx.doi.org/10.1186/1478-811X-11-42

Ejemplares similares

REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia
por: Cavadas, Miguel A. S., et al.
Publicado: (2015)

HIF-stabilizing biomaterials: from hypoxia-mimicking to hypoxia-inducing
por: Colombani, Thibault, et al.
Publicado: (2023)

The Importance of Hypoxia-Inducible Factors (HIF-1 and HIF-2) for the Pathophysiology of Inflammatory Bowel Disease
por: Kerber, Evelyn L., et al.
Publicado: (2020)

Regulation of the Hypoxia-Inducible Factor (HIF) by Pro-Inflammatory Cytokines
por: Malkov, Mykyta I., et al.
Publicado: (2021)

Hypoxia-Inducible Factor (HIF) in Ischemic Stroke and Neurodegenerative Disease
por: Mitroshina, Elena V., et al.
Publicado: (2021)

Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions
por: Burslem, George M., et al.
Publicado: (2017)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
por: Mole, David R., et al.
Publicado: (2009)

Induction of KSHV latency-associated nuclear antigen (LANA) by hypoxia and hypoxia-inducible factors (HIF)
por: Veeranna, Ravindra P, et al.
Publicado: (2012)

Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
por: Chan, Mun Chiang, et al.
Publicado: (2016)

The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans
por: Zhang, Yi, et al.
Publicado: (2009)

Hypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and Transactivity
por: Kietzmann, Thomas, et al.
Publicado: (2016)

Hypoxia-Inducible Factor-1 (Hif-1) in Experimental Brain Ischemia
por: Schmidt-Kastner, Rainald, et al.
Publicado: (2002)

Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?
por: Strowitzki, Moritz J., et al.
Publicado: (2019)

Hypoxia-inducible factor (HIF): The link between obesity and COVID-19
por: AbdelMassih, Antoine, et al.
Publicado: (2021)

Role of hypoxia inducible factor HIF-1α in heart valves
por: Georgy, Mark, et al.
Publicado: (2023)

Pathways of Hypoxia-Inducible Factor (HIF) in the Orchestration of Uterine Fibroids Development
por: Fedotova, Maria, et al.
Publicado: (2023)

Insights into Temperature and Hypoxia Tolerance in Cowpea Weevil via HIF-1
por: Liu, Qin, et al.
Publicado: (2021)

Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo
por: Baumann, Julia, et al.
Publicado: (2022)

Correction: Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions
por: Burslem, George M., et al.
Publicado: (2017)

Species differential regulation of COX2 can be described by an NFκB-dependent logic AND gate
por: Nguyen, Lan K., et al.
Publicado: (2015)

Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation
por: Martinez, Chloe-Anne, et al.
Publicado: (2022)

Hypoxia, HIF, and Associated Signaling Networks in Chronic Kidney Disease
por: Liu, Jing, et al.
Publicado: (2017)

GPT2 Is Induced by Hypoxia-Inducible Factor (HIF)-2 and Promotes Glioblastoma Growth
por: Zhang, Bo, et al.
Publicado: (2022)

Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells
por: Sethumadhavan, Shalini, et al.
Publicado: (2017)

Hypoxia-Inducible Factor (HIF) as a Target for Novel Therapies in Rheumatoid Arthritis
por: Hua, Susan, et al.
Publicado: (2016)

Hypoxia Inducible Factor (HIF) Hydroxylases as Regulators of Intestinal Epithelial Barrier Function
por: Manresa, Mario C., et al.
Publicado: (2017)

If it’s not one thing, HIF’s another: immunoregulation by hypoxia inducible factors in disease
por: Hammond, Ffion R., et al.
Publicado: (2020)

The Study of Expression of Hypoxia-Inducible Factor-1 Alpha (HIF-1 Alpha) and Hypoxia-Inducible Factor-2 Alpha (HIF-2 Alpha) in Oral Squamous Cell Carcinoma: An Immunohistochemical Study
por: Mahapatra, Niva, et al.
Publicado: (2023)

Oxygen-Independent Stabilization of Hypoxia Inducible Factor (HIF)-1 during RSV Infection
por: Haeberle, Helene A., et al.
Publicado: (2008)

Correction: Correction: Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions
por: Burslem, George M., et al.
Publicado: (2018)

Further Correction: Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions
por: Burslem, George M., et al.
Publicado: (2018)

Hypoxia Promotes Glycogen Accumulation through Hypoxia Inducible Factor (HIF)-Mediated Induction of Glycogen Synthase 1
por: Pescador, Nuria, et al.
Publicado: (2010)

Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans
por: Feng, Dingxia, et al.
Publicado: (2021)

A central role for hypoxia-inducible factor (HIF)-2α in hepatic glucose homeostasis
por: Ramakrishnan, Sadeesh K., et al.
Publicado: (2017)

Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia
por: Toth, Rachel K., et al.
Publicado: (2017)

Characterization and functional analysis of hypoxia-inducible factor HIF1α and its inhibitor HIF1αn in tilapia
por: Li, Hong Lian, et al.
Publicado: (2017)

Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function
por: Knowles, Helen J.
Publicado: (2020)

Hypoxia Inducible Factor (HIF) transcription factor family expansion, diversification, divergence and selection in eukaryotes
por: Graham, Allie M., et al.
Publicado: (2017)

Hypoxia Inducible Factor (HIF)-1 Coordinates Induction of Toll-Like Receptors TLR2 and TLR6 during Hypoxia
por: Kuhlicke, Johannes, et al.
Publicado: (2007)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_6gdfdq1ft1609mn6s7cmnr5dq8