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Allopurinol Use during Pregnancy - Outcome of 31 Prospectively Ascertained Cases and a Phenotype Possibly Indicative for Teratogenicity

Allopurinol is a purine analogue that inhibits xanthine oxidase. It is mainly used for the treatment of hyperuricemia in patients with gout or tumor lysis syndrome. Experience with allopurinol in pregnancy is scarce. In 2011, Kozenko et al. reported on a child with multiple malformations after mater...

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Detalles Bibliográficos
Autores principales: Hoeltzenbein, Maria, Stieler, Katja, Panse, Mary, Wacker, Evelin, Schaefer, Christof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686712/
https://www.ncbi.nlm.nih.gov/pubmed/23840514
http://dx.doi.org/10.1371/journal.pone.0066637