Suppression of Induced microRNA-15b Prevents Rapid Loss of Cardiac Function in a Dicer Depleted Model of Cardiac Dysfunction

BACKGROUND: Dicer endonuclease, critical for maturation of miRNAs, is depleted in certain forms of cardiomyopathy which results in differential expression of certain microRNAs. We sought to elucidate the mechanisms underlying the rapid loss of cardiac function following cardiac-specific Dicer deplet...

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Detalles Bibliográficos
Autores principales: Roy, Sashwati, Banerjee, Jaideep, Gnyawali, Surya C., Khanna, Savita, He, Guanglong, Pfeiffer, Douglas, Zweier, Jay L., Sen, Chandan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686742/
https://www.ncbi.nlm.nih.gov/pubmed/23840532
http://dx.doi.org/10.1371/journal.pone.0066789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686742/
https://www.ncbi.nlm.nih.gov/pubmed/23840532
http://dx.doi.org/10.1371/journal.pone.0066789

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