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Identification of Heat Shock Protein 60 as a Regulator of Neutral Sphingomyelinase 2 and Its Role in Dopamine Uptake

Activation of sphingomyelinase (SMase) by extracellular stimuli is the major pathway for cellular production of ceramide, a bioactive lipid mediator acting through sphingomyelin (SM) hydrolysis. Previously, we reported the existence of six forms of neutral pH–optimum and Mg(2+)-dependent SMase (N-SM...

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Detalles Bibliográficos
Autores principales: Ahn, Kyong-Hoon, Kim, Seok-Kyun, Choi, Jong-Min, Jung, Sung-Yun, Won, Jong-Hoon, Back, Moon-Jung, Fu, Zhicheng, Jang, Ji-Min, Ha, Hae-Chan, Kim, Dae-Kyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686747/
https://www.ncbi.nlm.nih.gov/pubmed/23840630
http://dx.doi.org/10.1371/journal.pone.0067216