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The ArfGEF GBF-1 Is Required for ER Structure, Secretion and Endocytic Transport in C. elegans

Small GTPases of the Sar/Arf family are essential to generate transport containers that mediate communication between organelles of the secretory pathway. Guanine nucleotide exchange factor (GEFs) activate the small GTPases and help their anchorage in the membrane. Thus, GEFs in a way temporally and...

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Detalles Bibliográficos
Autores principales: Ackema, Karin B., Sauder, Ursula, Solinger, Jachen A., Spang, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686754/
https://www.ncbi.nlm.nih.gov/pubmed/23840591
http://dx.doi.org/10.1371/journal.pone.0067076