Chemotherapeutic Potential of 2-[Piperidinoethoxyphenyl]-3-Phenyl-2H-Benzo(b)pyran in Estrogen Receptor- Negative Breast Cancer Cells: Action via Prevention of EGFR Activation and Combined Inhibition of PI-3-K/Akt/FOXO and MEK/Erk/AP-1 Pathways

Inhibition of epidermal growth factor receptor (EGFR) signaling is considered to be a promising treatment strategy for estrogen receptor (ER)-negative breast tumors. We have investigated here the anti-breast cancer properties of a novel anti-proliferative benzopyran compound namely, 2-[piperidinoeth...

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Detalles Bibliográficos
Autores principales: Saxena, Ruchi, Chandra, Vishal, Manohar, Murli, Hajela, Kanchan, Debnath, Utsab, Prabhakar, Yenamandra S., Saini, Karan Singh, Konwar, Rituraj, Kumar, Sandeep, Megu, Kaling, Roy, Bal Gangadhar, Dwivedi, Anila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686794/
https://www.ncbi.nlm.nih.gov/pubmed/23840429
http://dx.doi.org/10.1371/journal.pone.0066246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686794/
https://www.ncbi.nlm.nih.gov/pubmed/23840429
http://dx.doi.org/10.1371/journal.pone.0066246

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