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Bax and Bak have critical roles in ischemic acute kidney injury in global and proximal tubule-specific knockout mouse models
Bax and Bak, two pro-apoptotic Bcl-2 family proteins, have been implicated in acute kidney injury following renal ischemia/reperfusion; however, definitive evidence for a role of these genes in the disease process is lacking. Here we first examined two Bax-deficient mouse models and found that only...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686831/ https://www.ncbi.nlm.nih.gov/pubmed/23466994 http://dx.doi.org/10.1038/ki.2013.68 |