Activation of TLR3 in keratinocytes increases expression of genes involved in formation of the epidermis, lipid accumulation and epidermal organelles

Injury to the skin, and the subsequent release of non-coding double-stranded RNA from necrotic keratinocytes, has been identified as an endogenous activator of Toll-like receptor 3 (TLR3). Since changes in keratinocyte growth and differentiation follow injury, we hypothesized that TLR3 might trigger...

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Detalles Bibliográficos
Autores principales: Borkowski, Andrew W., Park, Kyungho, Uchida, Yoshikazu, Gallo, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686920/
https://www.ncbi.nlm.nih.gov/pubmed/23353987
http://dx.doi.org/10.1038/jid.2013.39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686920/
https://www.ncbi.nlm.nih.gov/pubmed/23353987
http://dx.doi.org/10.1038/jid.2013.39

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