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The Paradox of Akt-mTOR Interactions

The serine threonine protein kinase, Akt, is at the central hub of signaling pathways that regulates cell growth, differentiation, and survival. The reciprocal relation that exists between the two activating phosphorylation sites of Akt, T308 and S473, and the two mTOR complexes, C1 and C2, forms th...

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Detalles Bibliográficos
Autores principales: Vadlakonda, Lakshmipathi, Dash, Abhinandita, Pasupuleti, Mukesh, Anil Kumar, Kotha, Reddanna, Pallu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687210/
https://www.ncbi.nlm.nih.gov/pubmed/23802099
http://dx.doi.org/10.3389/fonc.2013.00165