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Expression of the Streptococcus pneumoniae pilus-1 undergoes on and off switching during colonization in mice

Streptococcus pneumoniae pili contribute to adherence and virulence. The regulation of pilus-1 expression is bistable, thus piliated strains contain a variable proportion of pilus-1-non-expressing bacteria. We investigated whether such proportion changes during colonization. Pilus-1-expressing bacte...

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Detalles Bibliográficos
Autores principales: Pancotto, Laura, De Angelis, Gabriella, Bizzarri, Esmeralda, Barocchi, Michèle A., Giudice, Giuseppe Del, Moschioni, Monica, Ruggiero, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687230/
https://www.ncbi.nlm.nih.gov/pubmed/23784148
http://dx.doi.org/10.1038/srep02040