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A Role for Fibroblast Growth Factor 19 and Bile Acids in Diabetes Remission After Roux-en-Y Gastric Bypass

OBJECTIVE: Roux-en-Y gastric bypass (RYGB) in humans can remit type 2 diabetes, but the operative mechanism is not completely understood. In mice, fibroblast growth factor (FGF) 15 (FGF19 in humans) regulates hepatic bile acid (BA) production and can also resolve diabetes. In this study, we tested t...

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Detalles Bibliográficos
Autores principales: Gerhard, Glenn S., Styer, Amanda M., Wood, G. Craig, Roesch, Stephen L., Petrick, Anthony T., Gabrielsen, Jon, Strodel, William E., Still, Christopher D., Argyropoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687273/
https://www.ncbi.nlm.nih.gov/pubmed/23801799
http://dx.doi.org/10.2337/dc12-2255