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Condensin controls recruitment of RNA polymerase II to achieve nematode X-chromosome dosage compensation

The X-chromosome gene regulatory process called dosage compensation ensures that males (1X) and females (2X) express equal levels of X-chromosome transcripts. The mechanism in Caenorhabditis elegans has been elusive due to improperly annotated transcription start sites (TSSs). Here we define TSSs an...

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Detalles Bibliográficos
Autores principales: Kruesi, William S, Core, Leighton J, Waters, Colin T, Lis, John T, Meyer, Barbara J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687364/
https://www.ncbi.nlm.nih.gov/pubmed/23795297
http://dx.doi.org/10.7554/eLife.00808