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MAPs: a database of modular antibody parts for predicting tertiary structures and designing affinity matured antibodies
BACKGROUND: The de novo design of a novel protein with a particular function remains a formidable challenge with only isolated and hard-to-repeat successes to date. Due to their many structurally conserved features, antibodies are a family of proteins amenable to predictable rational design. Design...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687570/ https://www.ncbi.nlm.nih.gov/pubmed/23718826 http://dx.doi.org/10.1186/1471-2105-14-168 |