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A Human/Murine Chimeric Fab Antibody Neutralizes Anthrax Lethal Toxin In Vitro

Human anthrax infection caused by exposure to Bacillus anthracis cannot always be treated by antibiotics. This is mostly because of the effect of the remaining anthrax toxin in the body. Lethal factor (LF) is a component of lethal toxin (LeTx), which is the major virulence of anthrax toxin. A murine...

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Detalles Bibliográficos
Autores principales: Ding, Guipeng, Chen, Ximin, Zhu, Jin, Duesbery, Nicholas S., Cheng, Xunjia, Cao, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687597/
https://www.ncbi.nlm.nih.gov/pubmed/23861692
http://dx.doi.org/10.1155/2013/475809