N-arachidonoyl glycine suppresses Na(+)/Ca(2+) exchanger-mediated Ca(2+) entry into endothelial cells and activates BK(Ca) channels independently of GPCRs

BACKGROUND AND PURPOSE: N-arachidonoyl glycine (NAGly) is a lipoamino acid with vasorelaxant properties. We aimed to explore the mechanisms of NAGly's action on unstimulated and agonist-stimulated endothelial cells. EXPERIMENTAL APPROACH: The effects of NAGly on endothelial electrical signallin...

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Detalles Bibliográficos
Autores principales: Bondarenko, Alexander I, Drachuk, Konstantin, Panasiuk, Olga, Sagach, Vadim, Deak, Andras T, Malli, Roland, Graier, Wolfgang F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687672/
https://www.ncbi.nlm.nih.gov/pubmed/23517055
http://dx.doi.org/10.1111/bph.12180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687672/
https://www.ncbi.nlm.nih.gov/pubmed/23517055
http://dx.doi.org/10.1111/bph.12180

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