Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis

The sphingolipid ceramide elicits several stress responses, however, organisms survive despite increased ceramide but how they do so is poorly understood. We demonstrate here that the AKT/FOXO pathway regulates survival in increased ceramide environment by metabolic adaptation involving changes in g...

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Detalles Bibliográficos
Autores principales: Nirala, Niraj K., Rahman, Motiur, Walls, Stanley M., Singh, Alka, Zhu, Lihua Julie, Bamba, Takeshi, Fukusaki, Eiichiro, Srideshikan, Sargur M., Harris, Greg L., Ip, Y. Tony, Bodmer, Rolf, Acharya, Usha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688504/
https://www.ncbi.nlm.nih.gov/pubmed/23818862
http://dx.doi.org/10.1371/journal.pgen.1003556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688504/
https://www.ncbi.nlm.nih.gov/pubmed/23818862
http://dx.doi.org/10.1371/journal.pgen.1003556

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