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Cohesin and Polycomb Proteins Functionally Interact to Control Transcription at Silenced and Active Genes

Cohesin is crucial for proper chromosome segregation but also regulates gene transcription and organism development by poorly understood mechanisms. Using genome-wide assays in Drosophila developing wings and cultured cells, we find that cohesin functionally interacts with Polycomb group (PcG) silen...

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Detalles Bibliográficos
Autores principales: Schaaf, Cheri A., Misulovin, Ziva, Gause, Maria, Koenig, Amanda, Gohara, David W., Watson, Audrey, Dorsett, Dale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688520/
https://www.ncbi.nlm.nih.gov/pubmed/23818863
http://dx.doi.org/10.1371/journal.pgen.1003560