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Distinct and Atypical Intrinsic and Extrinsic Cell Death Pathways between Photoreceptor Cell Types upon Specific Ablation of Ranbp2 in Cone Photoreceptors

Non-autonomous cell-death is a cardinal feature of the disintegration of neural networks in neurodegenerative diseases, but the molecular bases of this process are poorly understood. The neural retina comprises a mosaic of rod and cone photoreceptors. Cone and rod photoreceptors degenerate upon rod-...

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Detalles Bibliográficos
Autores principales: Cho, Kyoung-in, Haque, MdEmdadul, Wang, Jessica, Yu, Minzhong, Hao, Ying, Qiu, Sunny, Pillai, Indulekha C. L., Peachey, Neal S., Ferreira, Paulo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688534/
https://www.ncbi.nlm.nih.gov/pubmed/23818861
http://dx.doi.org/10.1371/journal.pgen.1003555