The NADPH Metabolic Network Regulates Human αB-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster

Dominant mutations in the alpha-B crystallin (CryAB) gene are responsible for a number of inherited human disorders, including cardiomyopathy, skeletal muscle myopathy, and cataracts. The cellular mechanisms of disease pathology for these disorders are not well understood. Among recent advances is t...

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Detalles Bibliográficos
Autores principales: Xie, Heng B., Cammarato, Anthony, Rajasekaran, Namakkal S., Zhang, Huali, Suggs, Jennifer A., Lin, Ho-Chen, Bernstein, Sanford I., Benjamin, Ivor J., Golic, Kent G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688542/
https://www.ncbi.nlm.nih.gov/pubmed/23818860
http://dx.doi.org/10.1371/journal.pgen.1003544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688542/
https://www.ncbi.nlm.nih.gov/pubmed/23818860
http://dx.doi.org/10.1371/journal.pgen.1003544

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