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Calreticulin-STAT3 Signaling Pathway Modulates Mitochondrial Function in a Rat Model of Furazolidone-Induced Dilated Cardiomyopathy

BACKGROUND: Calreticulin is a Ca(2+)-binding chaperone of the endoplasmic reticulum which regulates the signal transducer and activator of transcription 3 (STAT3). The effects of the calreticulin-STAT3 signaling pathway on cardiac mitochondria and on the progress of dilated cardiomyopathy (DCM) are...

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Detalles Bibliográficos
Autores principales: Zhang, Ming, Wei, Jin, Shan, Hu, Wang, Hao, Zhu, Yanhe, Xue, Jiahong, Lin, Lin, Yan, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688564/
https://www.ncbi.nlm.nih.gov/pubmed/23818963
http://dx.doi.org/10.1371/journal.pone.0066779