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Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis
ADP-dependent glucokinases represent a unique family of kinases that belong to the ribokinase superfamily, being present mainly in hyperthermophilic archaea. For these enzymes there is no agreement about the magnitude of the structural transitions associated with ligand binding and whether they are...
Autores principales: | Rivas-Pardo, Jaime Andrés, Herrera-Morande, Alejandra, Castro-Fernandez, Victor, Fernandez, Francisco J., Vega, M. Cristina, Guixé, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688580/ https://www.ncbi.nlm.nih.gov/pubmed/23818958 http://dx.doi.org/10.1371/journal.pone.0066687 |
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