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Tripeptidyl Peptidase II Regulates Sperm Function by Modulating Intracellular Ca(2+) Stores via the Ryanodine Receptor
Recent studies have identified Ca(2+) stores in sperm cells; however, it is not clear whether these Ca(2+) stores are functional and how they are mobilized. Here, in vitro and in vivo, we determined that tripeptidyl peptidase II antagonists strongly activated the cAMP/PKA signaling pathway that driv...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688596/ https://www.ncbi.nlm.nih.gov/pubmed/23818952 http://dx.doi.org/10.1371/journal.pone.0066634 |