A comprehensive analysis of AID's effects on the transcriptome and methylome of activated B cells

Beyond its well-characterized functions in antibody diversification, AID can catalyze off-target DNA damage and has been hypothesized to edit RNA and mediate DNA demethylation. To comprehensively examine AID's effects on the transcriptome and DNA methylome, we performed RNA-Seq and reduced-repr...

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Detalles Bibliográficos
Autores principales: Fritz, Eric L., Rosenberg, Brad R., Lay, Kenneth, Mihailović, Aleksandra, Tuschl, Thomas, Papavasiliou, F. Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688651/
https://www.ncbi.nlm.nih.gov/pubmed/23708250
http://dx.doi.org/10.1038/ni.2616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688651/
https://www.ncbi.nlm.nih.gov/pubmed/23708250
http://dx.doi.org/10.1038/ni.2616

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