The N-Terminal Domains of Vps3 and Vps8 Are Critical for Localization and Function of the CORVET Tethering Complex on Endosomes

Endosomal biogenesis depends on multiple fusion and fission events. For fusion, the heterohexameric CORVET complex as an effector of the endosomal Rab5/Vps21 GTPase has a central function in the initial tethering event. Here, we show that the CORVET-specific Vps3 and Vps8 subunits, which interact wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Epp, Nadine, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688683/
https://www.ncbi.nlm.nih.gov/pubmed/23840658
http://dx.doi.org/10.1371/journal.pone.0067307

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688683/
https://www.ncbi.nlm.nih.gov/pubmed/23840658
http://dx.doi.org/10.1371/journal.pone.0067307

Ejemplares similares