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RNAi Screening in Primary Human Hepatocytes of Genes Implicated in Genome-Wide Association Studies for Roles in Type 2 Diabetes Identifies Roles for CAMK1D and CDKAL1, among Others, in Hepatic Glucose Regulation

Genome-wide association (GWA) studies have described a large number of new candidate genes that contribute to of Type 2 Diabetes (T2D). In some cases, small clusters of genes are implicated, rather than a single gene, and in all cases, the genetic contribution is not defined through the effects on a...

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Detalles Bibliográficos
Autores principales: Haney, Steven, Zhao, Juan, Tiwari, Shiwani, Eng, Kurt, Guey, Lin T., Tien, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688709/
https://www.ncbi.nlm.nih.gov/pubmed/23840313
http://dx.doi.org/10.1371/journal.pone.0064946