Cargando…
Kinetic Proofreading at Single Molecular Level: Aminoacylation of tRNA(Ile) and the Role of Water as an Editor
Proofreading/editing in protein synthesis is essential for accurate translation of information from the genetic code. In this article we present a theoretical investigation of efficiency of a kinetic proofreading mechanism that employs hydrolysis of the wrong substrate as the discriminatory step in...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688713/ https://www.ncbi.nlm.nih.gov/pubmed/23840412 http://dx.doi.org/10.1371/journal.pone.0066112 |