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Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins
Cathepsin D (CD) plays an important role in both biological and pathological processes, although the cleavage characteristics and substrate selection of CD have yet to be fully explored. We employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify the CD cleavage sites in bovine...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688724/ https://www.ncbi.nlm.nih.gov/pubmed/23840360 http://dx.doi.org/10.1371/journal.pone.0065733 |