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Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins

Cathepsin D (CD) plays an important role in both biological and pathological processes, although the cleavage characteristics and substrate selection of CD have yet to be fully explored. We employed liquid chromatography-tandem mass spectrometry (LC-MS/MS) to identify the CD cleavage sites in bovine...

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Detalles Bibliográficos
Autores principales: Sun, Huiying, Lou, Xiaomin, Shan, Qiang, Zhang, Ju, Zhu, Xu, Zhang, Jia, Wang, Yang, Xie, Yingying, Xu, Ningzhi, Liu, Siqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688724/
https://www.ncbi.nlm.nih.gov/pubmed/23840360
http://dx.doi.org/10.1371/journal.pone.0065733