Systemic Autoimmunity in TAM Triple Knockout Mice Causes Inflammatory Brain Damage and Cell Death

The Tyro3, Axl and Mertk (TAM) triply knockout (TKO) mice exhibit systemic autoimmune diseases, with characteristics of increased proinflammatory cytokine production, autoantibody deposition and autoreactive lymphocyte infiltration into a variety of tissues. Here we show that TKO mice produce high l...

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Detalles Bibliográficos
Autores principales: Li, Qiutang, Lu, Qingjun, Lu, Huayi, Tian, Shifu, Lu, Qingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688737/
https://www.ncbi.nlm.nih.gov/pubmed/23840307
http://dx.doi.org/10.1371/journal.pone.0064812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688737/
https://www.ncbi.nlm.nih.gov/pubmed/23840307
http://dx.doi.org/10.1371/journal.pone.0064812

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