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A Novel Measure of Chromosome Instability Can Account for Prognostic Difference in Multiple Myeloma

Multiple myeloma (MM) is characterized by complex genetic abnormalities whose complexity signifies varying degree of chromosomal instability (CIN). In this study, we introduced a novel CIN measure, chromosome instability genome event count (CINGEC), which considered both copy number aberrations and...

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Detalles Bibliográficos
Autores principales: Chung, Tae-Hoon, Mulligan, George, Fonseca, Rafael, Chng, Wee Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688789/
https://www.ncbi.nlm.nih.gov/pubmed/23840451
http://dx.doi.org/10.1371/journal.pone.0066361