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A Novel Measure of Chromosome Instability Can Account for Prognostic Difference in Multiple Myeloma
Multiple myeloma (MM) is characterized by complex genetic abnormalities whose complexity signifies varying degree of chromosomal instability (CIN). In this study, we introduced a novel CIN measure, chromosome instability genome event count (CINGEC), which considered both copy number aberrations and...
Autores principales: | Chung, Tae-Hoon, Mulligan, George, Fonseca, Rafael, Chng, Wee Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688789/ https://www.ncbi.nlm.nih.gov/pubmed/23840451 http://dx.doi.org/10.1371/journal.pone.0066361 |
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