Inhibition of FLT3 Expression by Green Tea Catechins in FLT3 Mutated-AML Cells

Acute myeloid leukemia (AML) is a heterogeneous disease characterized by a block in differentiation and uncontrolled proliferation. FLT3 is a commonly mutated gene found in AML patients. In clinical trials, the presence of a FLT3-ITD mutation significantly correlates with an increased risk of relaps...

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Detalles Bibliográficos
Autores principales: Ly, Bui Thi Kim, Chi, Hoang Thanh, Yamagishi, Makoto, Kano, Yasuhiko, Hara, Yukihiko, Nakano, Kazumi, Sato, Yuko, Watanabe, Toshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688791/
https://www.ncbi.nlm.nih.gov/pubmed/23840454
http://dx.doi.org/10.1371/journal.pone.0066378

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688791/
https://www.ncbi.nlm.nih.gov/pubmed/23840454
http://dx.doi.org/10.1371/journal.pone.0066378

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