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Crystal Structure of Crataeva tapia Bark Protein (CrataBL) and Its Effect in Human Prostate Cancer Cell Lines

A protein isolated from the bark of Crataeva tapia (CrataBL) is both a Kunitz-type plant protease inhibitor and a lectin. We have determined the amino acid sequence and three-dimensional structure of CrataBL, as well as characterized its selected biochemical and biological properties. We found two d...

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Detalles Bibliográficos
Autores principales: Ferreira, Rodrigo da Silva, Zhou, Dongwen, Ferreira, Joana Gasperazzo, Silva, Mariana Cristina Cabral, Silva-Lucca, Rosemeire Aparecida, Mentele, Reinhard, Paredes-Gamero, Edgar Julian, Bertolin, Thiago Carlos, dos Santos Correia, Maria Tereza, Paiva, Patrícia Maria Guedes, Gustchina, Alla, Wlodawer, Alexander, Oliva, Maria Luiza Vilela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688800/
https://www.ncbi.nlm.nih.gov/pubmed/23823708
http://dx.doi.org/10.1371/journal.pone.0064426